| 초록 |
Previous diagnosis of disease is invasive and expensive, causing reluctance to patients. Therefore, a non-invasive sensors using sweat, respired breath, and saliva have gained attraction. In this study, a composite of polyethylene glycol (PEG) and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)-based conductive hydrogels was prepared as sensing base materials that can specifically detect Cathepsin D in sweat. Cathepsin D could be a useful biomarker for various diseases and is particularly known as one of the representative biomarker for Sarcopenia. It was confirmed that conductive hydrogels specifically react to Cathepsin D through tests to synthesize the Cathepsin D substrate in a conductive hydrogel and add Cathepsin D to determine the degree of fluorescence. It is expected that the disease can be easily diagnosed by detecting hormones non-invasive with conductive hydrogels. |
