| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Protein Adsorption and Bacterial Adhesion Resistance of Copolymerized Hydrogels based on Poly(2‐methacryloyloxyethyl phosphorylcholine) side chain and Poly(2-hydroxyethyl methacrylate ) backbone |
| 초록 |
A series of copolymerized hydrogels comprising various HEMA and MPC monomer formulations was prepared via a simple free-radical polymerization. The hydrogels demonstrated an improvement in the capability of retaining water content (79-202%) and indicated homogenous distribution of the MPC moieties as shown in the transmittance (＞90%) and contact angle measurements (67-70°). There is a remarkable enhancement in the anti-biofouling nature of the copolymerized hydrogels, partly due to the dense hydration shell formed by the zwitterionic MPC moieties at the surface of the hydrogels. The prepared hydrogels incurred a reduction in the lysozyme and bovine serum albumin (BSA) adsorption of about 44-65% and 40-70%, respectively. Overall, the results demonstrated the potential of copolymerization with phospholipid-based biomembrane-mimicking monomers as a workable route for the development of protein and bacterial resistant materials for biomedical and industrial applications |
| 저자 |
바돈 이사벨 웬1, 김호중1, Mai Khuong Duy2
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| 소속 |
1조선대, 2전남대 |
| 키워드 |
anti-biofouling; biomembrane-mimicking; copolymerization; hydrogel; protein adsorption
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| E-Mail |
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