| 초록 |
In general, gels are categorized according by solvents organogel and hydrogel. Recently, it has been classified more precisely such as supramolecular gels, metallogels etc., depending on the intermolecular interactions as well as solvents. One of the interesting points of the gel chemistry is that the gel behaves either as a solid or as a liquid depending on the conditions for forming the gel. Based on these behaviors, it has been used in various fields such as healthcare, tissue engineering, and cancer therapy. In this research, we introduce polymer gel system using hydrazon reaction between calix[4]arene and stilben derivative. In the prosess of this reaction, we try to load the Doxorubicin hydrochloride(DOX) as the drug for cancer. Frist, we checked the gelation adjusting some factors, heat time, exposing to ultraviolet rays or not, radiation time. Second, characteristic of gels was analyzed by SEM, rheology and so on. Finally, the ratio of drug release was analyzed by immersing gels to the solution using by Uv-vis. |
