| 학회 |
한국공업화학회 |
| 학술대회 |
2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
26권 1호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
Microfluidic system to monitor cell-cell interaction in a programmable static droplet array |
| 초록 |
Cell-cell interaction is related with biochemical signaling molecules and regulating a variety of biological responses such as quorum sensing, biofilm formation, and inflammatory response. In case of traditional cell culture systems there is difficult to accurately reproduce the effects of cell-cell interactions and well mix cell populations. Thus, this need to develop a novel platform for isolating, manipulating, tracking, and imaging cells to better study the various cell-cell interaction scenarios. Here we present a programmable static droplet array (SDA) for monitoring of the effect of population on natural cell-cell contact and signaling processes in a confined microenvironment. The SDA provides a valuable research tool to study cell-cell communication and signaling in a controlled microenvironment with the sensitivity and accuracy required for screening and long-term phenotypic analysis. |
| 저자 |
손희성, 김동영, 진시형, 이병진, 정성근, 이성식, Matthias Peter, 이창수
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| 소속 |
충남대 |
| 키워드 |
static droplet array; pneumatic valve; cell-cell interaction
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| E-Mail |
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