| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Glycerol/Silk Fibroin Film for Corneal Endothelial Cells |
| 초록 |
We designed transparent, stable silk films, well-degradable with glycerol as an alternative scaffold for bioengineering cornea. The morphological and structural properties were analyzed. In vitro biological compatibility was studied. FESEM images display the surface roughness and thickness by the various ratio mixtures of glycerol and SF. Glycerol content affected in transparency of each glycerol/SF films, but it is not significant except only glycerol film. Even though differences occur according to ratio of glycerol and SF, they do not show any significant differences on morphology and well-expressed their functional proteins which are regulated functions of CE. Overall, the results suggest that SF offers good environment on growth of CEnCs and glycerol plays a role to improve physical properties. glycerol/SF film may be a suitable alternative for high quality corneal tissue expansion and transplantation. This research was supported by NRF-2012M3A9C6050204 and BK21 PLUS. |
| 저자 |
강길선1, 주천기2, 김은영1, 심보라1, 국현1
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| 소속 |
1전북대, 2가톨릭 의과대 |
| 키워드 |
Glycerol; Silk fibroin; Corneal endothelial cell
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| E-Mail |
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