| 초록 |
Many studies about scaffold for peripheral nerve regeneration are conducted because peripheral nerve injury is one of important clinical disease for its complication of treatment. Among the many treatments for these injuries, the researches about scaffold that mimics ECM of nerve are more promising methods because of the limits of autograft. Recent studies of scaffolds in nerve regeneration show that topographical cue and electrical stimulation are important factors for guidance to nerve cells. To give more definite direction and guidance, We fabricate scaffold with conductivity on only line pattern. PEG hydrogel with conductive polymers is formed with patterns by UV irradiation. After that, PEG hydrogel is formed again by UV on the conductive hydrogel patterns. Through this simple techniques, the scaffolds can give more definite guidance to nerve cells because the nerve cells can be influenced by both topographical and electrical cues simultaneously. |
