화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관)
권호 34권 2호
발표분야 기능성 고분자
제목 The Anisometric Hydrogels of Photopolymerized Poly(N-isopropylacrylamide) and Drug Release Behavior of Temperature response
초록 Poly(N-isopropykacrylamide) (PNIPAAm) formed interpenetrating network (IPN) hydrogels with polyacrylamide (PAAm) or poly in the preparation of anisometric particles by Ultra Violet (UV) irradiation. The PNIPAAm-based hydrogels were prepared by using N,N’-methylenebisacrylamide of various concentrations as crosslinkers. 2-Hydroxy-1-[4-(hydroxyethoxy)-phenyl]-2-methyl-1-propanone (Irgacure2959) was used as a water soluble initiator. A freeze drying step was inserted into the two photocrosslinking steps of anisometric particles of IPN in order to photocrosslink PAAm in pre-crosslinked PNIPAAm hydrogels phases. Water soluble dyes were infiltrated into the resultant IPN hydrogels as a model active pharmaceutical ingredient. The swelling ratio of PNIPAAm/PAAm hydrogels was examined with loaded model drugs at various temperatures.
저자 이소나, 이종휘
소속 중앙대
키워드 photocrosslinking; PNIPAAm; hydrogel
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