| 초록 |
One of the most important tissue engineering methodologies is the combination of 3D scaffolds with autologous cells to produce bioimplants capable of promoting tissue regeneration. Poly lactic acid (PLA), approved by the FDA, has attracted much attention as a polymer scaffold for tissue engineering because of its good biodegradability, compostable characteristics. However, PLA is relatively bioinert, and has poor mechanical properties. This study was aimed to produce 3D printed PLA/calcium phosphate (CaP) composite scaffolds for by fused deposition modeling (FFF) process, and to examine the effect of the complexation of TCP or BCP and PLA on the mechanical and biological properties of the porous scaffolds for hard tissue engineering, in comparison with the pure PLA scaffolds. |
