| 초록 |
We have been studied cellular interactions on various polyelectrolyte multilayer film-coated surfaces. The results of those study indicated that the coatings having neutral or negatively charged hydrophilic surface exhibited excellent cell-blocking ability with non-cytotoxic nature. We applied these excellent biocompatible coatings with micro-contact printing for the study of cellular activities including adhesion, motility, proliferation, cell-cell networking both on open flat surface and on inner surfaces of micro-channeled devices. Multilayer films comprised of weak polyelectrolytes exhibit different surface properties as they were assembled at different pH conditions. Therefore, cellular interactions including adhesion can be shown differently by depending on the PEM surfaces. Polyelectrolytes including biodegradable polymers were investigated for this study, and we also include the potential application of this polymeric coating for membrane technology. |
