화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2022년 봄 (04/06 ~ 04/08, 대전컨벤션센터)
권호 47권 1호
발표분야 의료용 고분자 부문위원회
제목 Predominant Factor to Influence Cellular Behavior on Electrospun Nanofibrous Scaffolds. Wettability or Surface Morphology?
초록 In the present work, we have prepared two sets of polycaprolactone (PCL) based electrospun nanofibrous scaffolds, viz. surface morphology altered PCL scaffold (SMA PCL) with different surface morphology (P90, P80, and P70) and hydrophilic PCL-chitosan scaffold with different chitosan content (PC-a, PC-b, and PC-c). We further investigated the scaffolds' cell attachment and cell proliferation ability to find out which is a predominant factor, wettability, or surface morphology? From the results, we conclude that increasing the wettable property of a nanofibrous scaffold has been more influential in directing cellular behavior than surface morphology modification in the scaffold.
저자 강문성, Selestin Raja Iruthaya Pandi, 이석현, 장희정, 조효정, 한동욱
소속 부산대
키워드 Electrospun nanofiber; polycaprolactone; scaffold; wettability; surface morphology
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