| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Cyclosporin A release by using thermogel |
| 초록 |
Thermogel, consists of a combination of hydrophilic and hydrophobic moieties, is temperature-sensitive polymer and has unique properties. Unlike the phase transition that most liquids experience, the thermogel solution has the property of changing from sol to gel transition as the temperature increases. This property can be used for drug delivery system. Drug delivery system that allows drugs to be loaded into thermogel to create depot at the target site and enables local delivery of drugs has the advantage of being noninvasive procedure while treating, not requiring surgical surgery by injection. In addition, due to the sustained-release behavior of the drug loaded in the thermogel, it can be expected to reduce the frequency of dosing by injection and can effectively treat insoluble and short half-lives drugs. Here, we present a study of a thermogel with biodegradable polycaprolactone-based polymer that form depot in vivo and exhibit sustained release behavior of insoluble drugs. |
| 저자 |
이현정, ZHENGYU PIAO, 우예진, 정병문
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| 소속 |
이화여자대 |
| 키워드 |
drug delivery; controlled release; hydrogel
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| E-Mail |
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