| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 가을 (10/11 ~ 10/13, 제주컨벤션센터) |
| 권호 |
42권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Development of new immunoassay platform for Prostate specific antigen (PSA) detection using PCL/Ag/SiO2 nanostructure based on Metal-enhanced fluorescence effect of silver nanoparticles and wide surface area of nanofibers |
| 초록 |
Metal-enhanced fluorescence (MEF) is a phenomenon in which the fluorescence intensity is greatly improved by the interaction between surface plasmon resonance of metal nanoparticles such as gold or silver and fluorophores. In order to intensify the fluorescence signal a substrate with larger surface area is needed. It is also necessary to ensure adequate distance for the metal-enhanced flurescence effect. Thus to achieve that, the use of PCL/Ag/SiO2 nanostructure which is formed through electrospinning and stober method has been adopted. Due to Metal-enhanced fluorescence effect of silver nanoparticles and increased surface area by nanofiber structure, our system consequently yields a higher fluorescence signal and potentially provides a new immunoassay platform for Prostate specific antigen (PSA) detection. |
| 저자 |
윤병주, 조강희, 국윤민, 김경주, 고원건
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| 소속 |
연세대 |
| 키워드 |
Metal enhanced fluorescence effect; Silver nanoparticle; Nanofiber; Silica layer; Immunoassay
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| E-Mail |
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