| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
Adhesion and Proliferation Behavior of Retina Pigment Epithelial Cells on Silk Films with Various Boiling Time |
| 초록 |
Silk extracted from the cocoons has been used as biomaterials. These silk fibers are composed of fibroin and sericin surrounding fibroin. In case of fabricated silk film, sericin is normally removed during the degumming process because sericin is known to form fragile films. The silk films with various concentrations of sericin were fabricated by applying various boiling time (0, 20, 40 and 60). RPE cells were seeded on silk films and examined the influence on adhesion, proliferation and specific mRNA expression. This study demonstrated that produced silk films with various boiling time may serve as potential RPE cells' proliferation and structural basis for tissue engineered RPE cells. Therefore, we concluded that the silk film developed in this study has possibility of applications for future use on RPE cells. This research was supported by NRF-2012M3A9C6050204, Bio-industry Technology Development Program (KMFAFF, 112007-05-2-SB010) and the Brain Korea 12 PLUS Project, NRF. |
| 저자 |
양재원1, 이선의1, 김영래1, 김혜윤1, 조성준1, 송정은1, 김은영1, 주천기2, 이동원1, 강길선1
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| 소속 |
1전북대, 2가톨릭대 |
| 키워드 |
Silk; Retina Pigment Epithelial Cells; Scaffold; Tissue Engineering
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| E-Mail |
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