| 학회 |
한국고분자학회 |
| 학술대회 |
2004년 가을 (10/08 ~ 10/09, 경북대학교) |
| 권호 |
29권 2호, p.660 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Preparation and Characterization of Smart Magnetic Nanospheres and Their Effect on in vitro for MR Molecular Imaging |
| 초록 |
Magnetic resonance (MR) molecular imaging is an exiting new frontier in the biomedical applications of MR and is a noninvasive technique routinely used in diagnostic imaging. Also, noninvasive imaging of cell receptors is a powerful technique that enables early identification of lesions as well as repetitive measurements and more complete coverage, which is not feasible with invasive biopsy techniques. Recently nanoparticles are submicron - sized polymeric colloidal particles with a therapeutic or a diagnosis agent of interest encapsulated within their polymeric matrix or adsorbed or conjugated onto the surface. Also, intercellular targeting refers to the delivery of a therapeutic or a diagnosis agents to specific compartments or organelles within the cell. Superparamagnetic Iron Oxide Nanoparticles Encapsulated (IONE) could be used as efficient delivery vehicles for intracellular targeting. In this study, we propose here the use of peptides - conjugated IONE as a potent intracellular carrier for diagnosis agent and anti-body – conjugated IONE as a potent targeted MR contrast agent for diagnosis agent.
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| 저자 |
이승준1, 전봉식1, 허용민2, 송호택2, 서진석2, 김종득1
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| 소속 |
1한국과학기술원, 2연세대 |
| 키워드 |
MR Molecular Imaging; contrast agent; Magnetic Nanoparticle
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| E-Mail |
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