화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU))
권호 20권 2호
발표분야 (생물공학) 단백질공학의 최신 동향
제목 Identification and engineering of affinity peptides as molecular binder for detection of target biomarkers
초록 There is an urgent need for novel diagnostic methods capable of non-invasive, sensitive and feasible early prediction and detection of target biomarkers over conventional techniques. In this talk, I will be presented the use of phage display for the identification of novel peptide motifs that specifically recognize some of targets including colorectal cancer (CRC) biomarkers, human norovirus and sepsis biomarker and cholera toxin. A quartz crystal microbalance (QCM) is used as a diagnosis tool during biosensor development, and electrochemical techniques (cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS)) and surface-enhanced Raman scattering (SERS) are used as the detection methods in the biosensor.
저자 박종필
소속 대구한의대
키워드 phage display; affinity peptide; molecular binder; sensitivity; biosensor
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