| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
Dually cationic and anionic pH/temperature-sensitive multiblock copolymer as injectable hydrogel for protein delivery |
| 초록 |
Novel dually ionic multiblock copolymers that containing either cationic pH-sensitive tertiary-amines, anionic pH-sensitive sulfonamides and temperature-sensitive triblocks poly(e-caprolactone-co-lactide) – poly(ethylene glycol) – poly(e-caprolactone-co-lactide) were developed. These copolymers displayed a round shape and close-loop sol-gel-sol phase transition diagram due to amphoteric pH-sensitive properties. The rheological properties, in-vivo gelation and degradation were also investigated to demonstrate potential application as injectable hydrogel system for drug/protein delivery. |
| 저자 |
NGUYEN QUANG VINH, 이두성
|
| 소속 |
성균관대 |
| 키워드 |
hydrogel; polymeric biomaterial; pH/temperature-sensitive; drug/protein delivery
|
| E-Mail |
|
