| 학회 |
한국공업화학회 |
| 학술대회 |
2012년 가을 (10/31 ~ 11/02, 대전컨벤션센터) |
| 권호 |
16권 2호 |
| 발표분야 |
포스터-고분자 |
| 제목 |
Catechol-grafted dextran for anti-fouling surface modification of metal implants |
| 초록 |
Surface modification of material to prevent protein adsorption is one of the main issues in the study of prosthetics. There have been various attempts to give antifouling ability to the material for medical implantation; however, insufficient stability and degradation due to the aqueous environment made it difficult to maintain the desired effects. Here, we propose catechol-grafted dextran as a promising coating material for metallic implant materials. Catechols were conjugated to dextran at various grafting densities of catechol to dextran. Titanium dioxide was coated with catechol-grafted dextran via strong adhesive capability of catechol. The surface-modified titanium dioxide was subsequently tested to examine the anti-fouling effect against serum albumin and showed excellent resistance to non-specific protein adsorption. It is expected that catechol-grafted dextran has high potential as a surface coating material for a wide range of implant materials. |
| 저자 |
박재윤1, 김지선2, 남윤성1
|
| 소속 |
1한국과학기술원 신소재공학과, 2한국과학기술원 생명과학과 |
| 키워드 |
Anti-fouling; Dextran; Catechol
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| E-Mail |
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