| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 가을 (11/02 ~ 11/04, 경원대학교) |
| 권호 |
15권 2호 |
| 발표분야 |
나노 |
| 제목 |
Highly Stable and Biocompatible Nanoparticles through VersatileMulti-interaction Ligands inspired by Mussel Adhesive Protein |
| 초록 |
Inspired by mussel adhesive protein, we herein report on the designed synthesis of versatile multi-interaction ligand (MIL) by combining poly(ethylene glycol), polyethylenimine and polyDOPA for ultrastable and biocompatible nanoparticles. The MIL can stabilize various nanoparticles of metals and metal oxides by various cooperative binding modes. The MIL stabilized nanoparticles of Fe3O4, MnO, and Au exhibited extremely high stability in various harsh aqueous environments. The synthetic procedure is easy to scale-up, and the ligand exchange process is very simple and short. The successful in vivo MRI application using MIL-functionalized Fe3O4 confirmed its suitability for various biomedical applications. |
| 저자 |
릉대순1, 현택환2
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| 소속 |
1World Class Univ. (WCU) program of Chemical Convergence for Energy & Environment (C2E2) and School of Chemical and Biological Engineering, 2Seoul National Univ. |
| 키워드 |
nanoparticles; ligand; mussel; biocompatibility; contrast agent
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| E-Mail |
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