화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터)
권호 38권 2호
발표분야 기능성 고분자 (포스터발표만 진행)
제목 Preparation and release kinetics of biological substances from silk fibroin film
초록 Silk has been used as a polymeric drug carrier in several different forms. This polymer presents many advantages for controllable polymeric release systems such as biocompatibility, biodegradability, and aqueous processing. Caffeine has been used in cosmetics in order to stimulate the fat body metabolism, and many commercialized sliming creams contain caffeine as a main ingredient. On the other hand, phytoncides emitted from trees have the properties of stress relieving, skin whitening, anti-microbial and anti-oxidant. Transdermal therapeutic systems have many advantages over the traditional topical formulations such as control of the area of application and amount of dose. Therefore, transdermal delivery using bio-adhesive film is a good method for the administration of biological substances. In this study, we prepared silk fibroin films containing caffeine and phytoncides as a biological substance for transdermal patches and the kinetics of release was investigated.
저자 윤나경, 이기훈, 김무곤, 곽효원, 이정윤, 윤해성, 김민화, 양예솔
소속 서울대
키워드 caffeine; phytoncide; silk; film
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