| 초록 |
In this study, we control nano gaps between two Au@Ag nanoparticles on the surface of Au-Ag alloy embedded silica nanoparticle (SiO2@Au@Ag) and used them as a highly sensitive nanoprobe for surface-enhanced Raman scattering. The Ag shell was grown on the surface of SiO2@Au nanoparticles by reducing Ag ion and the narrow gaps were formed between two Au@Ag nanoparticles on the surface of the nanoprobes. At the nano-gap, SiO2@Au@Ag showed strong Raman signals derived from enhanced E-field. As a result, SERS activities of the NPs were tuned by adjusting AgNO3 concentration. As application, the SiO2@Au@Ag could detect ATP up to 2.4 nM, which demonstrate the probes are highly sensitive. Also, ATP Raman signals of the SiO2@Au@Ag was reproducible. Thus, SiO2@Au@Ag is promising for potential of SERS substrate and could be utilized as a sensitive SERS probe in various fields. |
