화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2014년 가을 (11/12 ~ 11/14, 엑스코(대구))
권호 18권 2호
발표분야 생물공학-포스터
제목 Enzymatic hydrolysis of casein to improve bioavailability of cacium(Ca) and magnesium(Mg)  
초록 Mineral supplements are required to be soluble as their bioavailability is highly correlated to their solubility in body fluids. However, calcium (Ca) and magnesium (Mg) form insoluble precipitate in a neutral and alkaline pH. To improve the bioavailability of Ca and Mg, it is necessary to enhance solubility at neutral and alkaine pH. In this study, we hydrolyze casein by using enzymes. Protein hydrolysate has a free amino acid functional groups and make chelates with Ca and Mg ions and then prevent to form insoluble precipitates. Optimized conditions for casein hydrolysis  such as enzyme type, enzyme/substrate ratio and hydrolysis time are investigated to make a chelates with Ca and Mg ions. By addition of casein hydrolysate, Mg solubility increased from 80 to 100 and that of Ca increased from 1.2 to 25% at pH 8. Casein hydrolysate addition shows great improvement on Mg and Ca bioavailability.
저자 홍혜진, 박인수, 류태공, 류정호, 김병규, 정강섭
소속 한국지질자원(연)
키워드 magnesium; calcium; absorbtion; solubility; casein hydrolysate; solubility
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