| 초록 |
Cell encapsulation needs to provide immunoprotection for transplanted cells. Alginate is a good candidate to protect transplanted cells from immune rejection and as a matrix to increase the cell viability. However alginate doesn't have sufficient mechanical and chemical resistance properties to achieve long-term transplantation. In this study, we designed alginate-cellulose membrane for cell encapsulation. 2,2,6,6-tetramethylpiperidine-1-oxylradical (TEMPO)-mediated oxidized bacterial cellulose (BC) was used to obtain improved membrane properties for cell encapsulation. BC produced by bacteria, has extraordinary potential as functional bio-composite materials. Carboxyl groups on the surface of TOBC provided the possibility of participating in the construction of an alginate based membrane structure and played important roles in the structural, mechanical and chemical stability. |
