| 학회 |
한국고분자학회 |
| 학술대회 |
2003년 가을 (10/10 ~ 10/11, 부경대학교) |
| 권호 |
28권 2호, p.166 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
In vitro and in vivo biocompatibility of cross-linked hydrogels by γ-ray irradiation technique |
| 초록 |
In this work, a series of hydrogels, PVA, PVP, blendmer of PVA and PVP (PVA/PVP), blendmer of PVA/PVP and chitosan (PVA/PVP/chitosan), blendmer of PVA/PVP and gelatin (PVA/PVP/gelatin), and blendmer of PVA/PVP and alginate (PVA/PVP/alginate) were prepared by Co gamma-ray irradiation. The biocompatibility of these hydrogels was evaluated (i) in vitro in cultures of mouse fibroblasts, and (ii) in vivo by subcutaneous implantation studies in rats. The cytotoxicity of these hydrogels was compared by measuring cell survival with the tetrazolium salt reduction (MTT) assay after incubations of fibroblasts for 48 hours in the presence of extracts of hydrogels. In vitro, the degree of cytotoxicity of g |
| 저자 |
전흥재1, 남상용2, 노영창3, 채규태4, 장홍석5, 유규은6, 서태석7
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| 소속 |
1가톨릭의대 생명의과학과, 2경상대, 3원자력 (연), 4가톨릭의대 병리학교실, 5가톨릭의대 치료방사선과, 6가톨릭의대 의생물학과, 7가톨릭의대 생체의공학(연) |
| 키워드 |
hydrogel |
| E-Mail |
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