화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU))
권호 22권 2호
발표분야 정밀화학_포스터
제목 Synthesis of N-carbamoylpropagylamines from α-Amidoalkyl sulfone and Alkynyldimethylaluminum prepared from terminal alkynes and trimethylaluminum
초록 Propargylamines are a versatile class of compounds whose application in pharmacological and pharmaceutical chemistry has soared. Generally, propagylamines are synthesized from by simple alkylation reactions such as amination of propargylic halides, propargylic phosphates, or propargylic triflates. We have synthesized N-carbamoylpropargyl amines prepared from variety of α-Amidoalkyl sulfone were reacted with alkynylaluminum reagents to provide desired products in excellent yield.
저자 이지훈, 이상협
소속 대구가톨릭대
키워드 aluminum reagent; propagylamine
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