| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Synthesis and Characterization of Novel Self-Assembled Brush copolymers Bearing Glucose Moieties |
| 초록 |
A new series of chemically well-defined brush glycopolymers consisting of a polyoxyethylene backbone and bristles bearing glycosyl and methyl end groups was synthesized with various compositions. The brush polymer films formed multibilayer structures, the layers of which were stacked along the direction normal to the film plane so as to display a glycosyl group-rich surface or a methyl group-rich surface or their mixture, depending on the bristle end group composition. The glycosyl-rich surface played a critical role in enhancing the surface hydrophilicity and water sorption to a certain level; thus, theglycopolymer films easily formed a hydration layer to a certain depth on the film surface. The hydrophilic surfaces and hydration layer efficiently prevented protein adsorption onto the brush glycopolymers and suppressed bacterial adherence while promoting mammalian cell adhesion and displaying excellent biocompatibility in an in vivo mouse study. |
| 저자 |
권경호1, 김진철1, 노예철1, 김가희1, 김미희1, 김경태1, 고용기1, 정성민1, 김종현1, 이진석1, 송성진1, 이종찬1, 이호열1, 김영용1, 위동우1, 김창섭1, 김용진1, 김희수2, 김익정2, 김정란2, 이문호1
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| 소속 |
1포항공과대, 2동국대 |
| 키워드 |
Brush polymer; glucopolymer; glucose
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| E-Mail |
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