| 초록 |
Although most of cataract surgery is performed by removal of natural lens, followed by implantation of foldable IOL, there is still a demand for injectable IOL that can be placed through an even smaller incision and preserves accommodation. Silicone compounds are appropriate material as an injectable IOL in terms of refractive index, elasticity, non-toxicity, transparency, and biocompatibility. However, silicones as well as other hydrophobic polymers suffer from the posterior capsule opacification (PCO) which remains the most common cause of vision loss after a cataract surgery. In this study, silicone prepolymers were modified by grafting with hydrophilic poly(ethylene glycol) to produce silicone-g-PEG polymers whether to prevent PCO. The silicone or silicone-g-PEG polymers were in-situ cured via hydrosilylation reaction. The rate of gelation and mechanical properties were characterized by a rheometer. |
