초록 |
Dopamine (DA) is a type of neurotransmitter, abnormal changes in dopamine concentrations could cause serious diseases such as sleeping and eating disorders, Parkinson’s disease, and addictive behaviors associated with drug abuse. In this study, we suggested an oxygen plasma treatment ruthenium nanoparticle-immobilized multiscale pore-containing carbon nanofiber (Ru-MPCNF)-based field-effect transistor (FET) nonenzymatic sensor to detect DA. The porous carbon structure not only promotes the generation of small-size Ru particles but also induces a large active surface area for dopamine. The nonenzymatic sensor electrode showed high sensitivity to DA as low as 1 fM, even in the presence of interfering biomolecules. Moreover, the sensor electrode also displayed stable sensing performance with long lifetimes due to the nonbiological working mechanism. |