| 학회 | 한국화학공학회 |
| 학술대회 | 2008년 가을 (10/23 ~ 10/24, 부산 BEXCO) |
| 권호 | 14권 2호, p.3616 |
| 발표분야 | 제5회 약물전달(DDS) 기술 심포지엄 |
| 제목 | Colloidal Drug Delivery Systems; Its Potentials and Applicationsin the Pharmaceutical Area |
| 초록 | Colloidal drug delivery systems have been applied in pharmaceutical area for its potentials for oral delivery, skin permeation enhancement and targeting of the therapeutic drugs. Many kinds of colloidal drug delivery systems including liposome, microemulsion, micelle system and solid lipid nanoparticle are reported for these purposes because they are able to solubilize, enhance the bioavailability of poorly water soluble drugs, control the drug release profiles, enhance trans-biomembrane permeation and give targetability functions toward specific organ and cells. We have studied about the potentials of the colloidal drug delivery systems in the view point of skin permeation, enhancement of solubility and bioavailabilityemploying liposome, microemlsion, polymeric micell and solid lipid nanoparticle using ascorbyl palmitate, ibuprofen, nitroglycerin and genistein asmodel drugs. |
| 저자 | 전상옥, 황희진, 이상길 |
| 소속 | 인제대 |
| 키워드 | Colloidal drug delivery systems; liposomes; microemulsion; micell |
| 원문파일 | 초록 보기 |
