| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
[무기재료] 키랄나노소재의 새로운 가치 및 응용 |
| 제목 |
The organic materials recognizing the chirality of biomolecules |
| 초록 |
A novel multifunctional aminophenylboronic acid connected to a diphenylketone gives both circular dichroism and fluorescence signals by in situ generation of a BODIPY-like chromophore in the presence of aminoalcohols. DFT calculations were used to understand the role of each functional group in the mechanism. This new sensor can distinguish different aminoalcohols and quantitatively indicate the concentration of the substrate, allowing for the convenient determination of the ee of racemic mixtures with a single probe. This probe can be devloped as a novel click sensor for the recognition and imaging of biomolecules. |
| 저자 |
김관묵, Mijin Kwak
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| 소속 |
이화여자대 |
| 키워드 |
Chirality; Circular Dichroism; Click Sensor; Fluorescence imaging
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| E-Mail |
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