화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2005년 봄 (04/14 ~ 04/15, 전경련회관)
권호 30권 1호, p.668
발표분야 의료용 고분자 부문위원회
제목 A three-dimensional nanofiber gelatin scaffold for skin tissue engineering using epidermal stem cell
초록 Electrospinning is a fabrication process that uses an electric field to control the deposition of polymer fibers onto a target substrate. This electrospinning processing strategy can be used to fabricate fibrous polymer mats composed of fiber diameters ranging from several microns down to 500 nm or less. In this study, An electrospinning method was used to gelatin nanofiber non wovens for cell culture of normal rat epidermal stem cells. The electrospinning of regenerated gelatin was performed with 2,2,2-trifluoroethanol as a spinning solvent. To assay the cell behavior onto the electrospun gelatin nanofibers, cell attachment and spreading of normal rat epidermal stem cells seeded on the gelatin nanofibers and interaction between cells and gelatin nanofibers were studied. The structural, material, and biological properties of electrospinning gelatin suggest that this material may represent a nearly ideal tissue engineeing scaffold.
저자 정성인, 이영무
소속 한양대
키워드 tissue engineering; Electrospinning; epidermal stem cell
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