| 초록 |
The poly(methyl methacrylate) (PMMA) resin was studied for the orthodontic retainer due to its good mechanical strength and biocompatibility, but its commercialization was limited due to lack of anti-bactieral property. To overcome the limitation, incorporating the zwitterion inert to nonspecific adsorption with resin is most investigated. However, the incorporated PMMA resin showed lower mechanical strength than bare resin. In this study, we tuned between the inertness to nonspecific adsorption and the mechanical strength of resin by grafting of zwitterion, 2-Methacryloyloxyethyl phosphorylcholine (MPC). MPC grafted PMMA resin reduced the nonspecific adsorption and had similar mechanical strength with bare resin. Improved hydration ability of resin was achieved by the addition of 2.5M NaCl, consequently, resin reduced almost 80% of bacterial adsorption compared with the bare resin. Furthermore, the MPC grafted PMMA resin showed mechanical strength complying ISO 20795-2. |
