| 학회 | 한국화학공학회 |
| 학술대회 | 2010년 봄 (04/22 ~ 04/23, 대구 EXCO) |
| 권호 | 16권 1호, p.394 |
| 발표분야 | 생물화공 |
| 제목 | Photo-patterning of inverted opal pHEMA for biosensor |
| 초록 | pHEMA(poly(2-hydroxyethylmethacrylate)) has some advantage to use for biosensor. Protein activity can be more increasing because of soft surface of pHEMA. In addition, pHEMA has plenty of hydroxyl group, so its surface modification is easy. Furthermore, inverted opal pHEMA has much more surface area than pHEMA, so lots of protein can be adsorbed pHEMA. Consequently, sensitivity of biosensor can be enhanced. Poly styrene(PS) particle can be easily dissolved in chloroform. Adopting this property, it is possible to make inverted opal pHEMA hydrogel irradiating UV to pHEMA and PS particle mixture after covering photomask. Then, we put patterned-hydrogel into chloroform to dissolve PS particle. Finally, porous pHEMA is fabricated. As comparing fluorescence intensity between pHEMA and inverted opal pHEMA, we can observe and determine whether inverted opal pHEMA has stronger intensity than pHEMA. Interconnected 3D biosensor which is enhanced sensitivity can be manufactured using this fabrication method. |
| 저자 | 이영민, 이 열, 박상필, 장은지, 박새미, 이현종, 남승희, 손경진, 박영하, 고원건 |
| 소속 | 연세대 |
| 키워드 | HEMA; inverted opal; PS particle; protein fluorescence intensity; photo-patterning |
| 원문파일 | 초록 보기 |
