| 학회 |
한국공업화학회 |
| 학술대회 |
2013년 가을 (10/30 ~ 11/01, 대전컨벤션센터) |
| 권호 |
17권 2호 |
| 발표분야 |
포스터-고분자 |
| 제목 |
Ionizing radiation-based micropatterning of antifouling poly(N-isopropyl acrylamide) films for the spatial inhibition of cell adhesion |
| 초록 |
In this study, a facile ionizing radiation-based method for the micropatterning of antifouling films on polymer surface for spatial inhibition of cell adhesion was investigated. The poly(N-isopropyl acrylamide) (PNIPAAm) thin films formed on tissue culture polystyrene (TCPS) dishes by spin coating were selectively irradiated by energetic ions at different fluences through a pattern mask, and then developed to generate the negative patterns of PNIPAAm on TCPS surfaces. The results of the surface analysis revealed that well-defined negative patterns of PNIPAAm were successfully generated on the dishes above the fluence of 5 x 1014 ions/cm2. Furthermore, the result of the cell culture test exhibited that 100 µm cell patterns were effectively formed on PNIPAAm-pattered TCPS substrates due to the strong antifouling effect of PNIPAAm patterns. |
| 저자 |
정진묵1, 황인태2, 정찬희2, 최재학3, 신관우1
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| 소속 |
1서강대, 2한국원자력(연), 3충남대 |
| 키워드 |
Ion irradiation; PNIPAAm; antifouling; cell adhesion
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| E-Mail |
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