화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO))
권호 22권 1호
발표분야 생체재료_포스터
제목 Biomineralization Mechanism on Collagen for Bone Tissue Applications  
초록 Collagen (COL) is a protein constituting about 30% of total protein content in human body. In addition, COL is a major organic phase of natural bone. Hydroxyapatite (HA) has been widely used as bone substitutes since HA displays chemical structure similar to bone. On the other hand, the bone formation mechanism has not been well-explored so far although bone is formed via HA mineralization on COL fiber. In this study, we investigated bone mineralization mechanism under the biomimetic environment. COL film was prepared and film surface was used for the mineralization of amorphous apatite. It was attempted to incorporate metallic trace element in the mineralization process. The mineralized COL morphology and chemical state were analyzed using SEM and EDS.
저자 홍재윤, 고숙영, 김태연, 배승훈, 이슬, 양혜윤, 조경철, 이우걸
소속 단국대
키워드 Collagen; biomineralization; bone formation
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