| 초록 |
The red ketocarotenoid astaxanthin (3,3’-dihydroxy-β, β-carotene-4,4’-dione) is not only used as a pigmentation source for fish aquaculture and food industry, but also has potential clinical applications due to its higher antioxidant activity than those of β-carotene and vitamin E. Although a few microorganisms such as Phaffia rhodozyma are capable of synthesizing astaxanthin, their cellular astaxanthin concentrations are very low (≤ 0.4%). By contrast, the freshwater microalga Haematococcus pluvialis accumulates more than 4% astaxanthin during the transformation to the aplanospore stage as a response to stress conditions. The astaxanthin accumulation in the H. pluvialis can be induced by nitrogen-limitation, strong light intensity, high temperature, pH, salinity, or phosphate deficiency. In this study, the productivity of astaxanthin from four kinds of H. pluvialis strains was compared under nitrogen deprivation and high light intensity. H. pluvialis UTEX 16, UTEX 2505, CCAP 34/7, and NIES 144 were cultured on each optimal medium in 250 ml Erlenmeyer flasks. It was also investigated that effect of CO2 concentration on growth rate of H. pluvialis and astaxanthin accumulation. |
