| 초록 |
The aim of the current study is to engineer perfusable vascular network using Catton candy machine and 3D printing techniques in co-culture of pro-angiogenic cells (e.g. vascular endothelial cells and pericyte function cells). This template is designed to enable anastomosis between the synthetic networks and host blood vessels through structural guidance and angiogenesis, thereby aiding regeneration of largely damaged tissues from combat wounding and traffic accidents through patch-formatted implantation. In addition, shape memory polymers (SMPs) and 3D printing can be combined to enable 4D printing for programmable guidance of tissue growth. The feasibility and methodology will be presented here. This study was financially supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (2016M3A9E9941743). |
