화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2004년 가을 (10/08 ~ 10/09, 경북대학교)
권호 29권 2호, p.668
발표분야 의료용 고분자 부문위원회
제목 Poly(ester amide)s backbone polymer base on arginine
초록 The purpose of this research was to synthesize new regular poly(ester amide)s (PEAs) consisting of hydrophilic α-amino acid, α,ω-diols, and aliphatic dicarboxylic acids, and to examine the effects of the structure of these building block components on some physico-chemical and biochemical properties of the polymers. PEAs were prepared by solution polycondensation of esterification of bis-(α-amino acid) α,ω-alkylene diesters and di-p-nitrophenyl esters of diacids. And the property of PEAs derived arginine which releases nitric oxide gas is studied. Because PEAs derived from arginine were expected to be revealed properties of arginine monomer, hydrolysis of these new PEA substrates was studied to assess the effect of the building blocks of these new polymers on their biodegradation properties in vitro.
저자 정철1, 안철희1, 이근호2, 홍순만2, 황승상2, 한동근2, 김광웅2
소속 1서울대, 2한국과학기술(연)
키워드 poly(ester amide)s; arginine
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