| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
고분자가공/복합재료 |
| 제목 |
Silk Fibroin Composite Hydrogels Prepared by Enzymatic Crosslinking System |
| 초록 |
Hydrogels have become attractive in the tissue engineering field because of its water-swollen properties and possibilities to mimicking extracellular matrix(ECM). For fabricating polymeric network systems for hydrogels, it is necessary to adopt a variety of physical or chemical crosslinking strategies. Among these methods, enzymatic crosslinking has the advantage of a few side effects due to enzyme-substrate specificity and mild reaction conditions. Mainly, horseradish peroxidase(HRP) is widely used for preparing hydrogels by catalyzing redox reaction and radical coupling between phenol groups which are abundant in many proteins like silk fibroin(SF). Therefore, many HRP-crosslinked SF hydrogels have been reported not only SF only hydrogels but also conjugates with other biopolymers. In this study, we prepared SF composite hydrogels by H2O2/HRP system with another biopolymer and structural/mechanical properties of hydrogels were investigated. |
| 저자 |
전경화, 김정수, 이현지, 김지환, 양세준, 이기훈
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| 소속 |
서울대 |
| 키워드 |
Silk; Hydrogel; Horseradish peroxidase; Enzymatic crosslinking
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| E-Mail |
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