| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터) |
| 권호 |
43권 2호 |
| 발표분야 |
대학원생 구두발표(발표15분) |
| 제목 |
One-pot synthesis of a zwitterionic small molecule bearing disulfide moiety for anti-biofouling macro and nanoscale gold surfaces |
| 초록 |
The goal of this study is to develop a one-pot synthesis of a zwitterionic small molecule which provides effective anti-biofouling properties on macroscopic and nanoscopic gold surfaces. To this end, a zwitterionic small molecule was successfully synthesized by utilizing dipyridyl disulfide in a one-pot method. The coating conditions and stablity were examined through contact angle measurements, surface plasmon resonance (SPR), and X-ray photoelectron spectroscopy. The anti-biofouling properties of the coated gold surface were analyzed by FITC-bovine serum albumin (BSA) test and SPR as contacting with BSA solution. In addition, the effect of zwitterion-coating on stability of and protein adsorption on gold nanoparticles were examined through a NaCl stability test and BSA adsorption test, respectively. As a result, simply synthesized zwitterionic small molecule effectively enhanced the anti-biofouling properties gold surfaces and the salt stability of gold nanoparticles. |
| 저자 |
이승주1, 이원규1, 박지호2, 이재승1, 서지훈1
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| 소속 |
1고려대, 2서강대 |
| 키워드 |
small molecule; protein adsorption; zwitterion; anti-biofouling; gold substrate; gold nanoparticle; salt stability
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| E-Mail |
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