화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO))
권호 23권 1호
발표분야 생체재료_포스터
제목 Synthesis of zwitterionic and tetra-fluorinated polyurethane additives for enhancing anti-fouling and anti-thrombotic effect
초록 We designed novel zwitterionic and tetra-fluorinated polyurethane (ZFPU) additives to confer anti-fouling and anti-thrombotic effects and blended these with polyvinyl chloride (PVC). 1HNMR and FTIR analyses showed that the zwitterionic groups and fluorinated groups were successfully introduced onto the ZFPU backbone. We also investigated the protein adsorption, platelet adhesion and wettability of additives-blended PVC films. Our results demonstrated that the ZFPU additives-blended PVC surfaces significantly suppressed protein adsorption and platelet adhesion than those of pristine PVC surface. Based on these results, it is expected that our novel additives will be promising for various biomaterials, including blood-contacting medical devices.
저자 최수연1, 강종희1, 임충만1, 고원건2, 정윤기1
소속 1한국과학기술(연), 2연세대
키워드 zwitterion; fluorinated materials; anti-fouling; anti-thrombotic effect; polyurethane additives
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