| 초록 |
Overcoming the recent drawbacks for detection the presence of cells on the surface, a pH-switchable zwitterionic polymer dot (PD) is proposed here as a fast and efficient method to detect and control the biological adhesion of cells and bacteria in accordance with fluorescent ON/OFF phenomena and electrochemical signals generated. The surfaces coated with PD showed high sensitivity under different pH conditions, expressing effective resistance to cellular attachment in acidic and basic environments as well as ionic interactions with the bacterial surface. These interactions could be identified rapidly and with high accuracy by analyzing the fluorescent behavior and current signal generated by cyclic voltammetry. Therefore, PD-coated surfaces represent as a smart surface to visualize and controll biological cell attachment with high sensitivity, biocompatibility, selectivity, and accuracy. This work was supported by Korea National University of Transportation in 2019. |
