| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Development of mechanically enhanced Triple interpenetrating polymer network hydrogels(PEG/PAA/PAM) for artificial cornea. |
| 초록 |
Hydrogels are attractive materials for biomedical applications due to their versatility and excellent biocompatibility. But, It is not suitable for biomedical applications which requires high mechanic strength. In this experiment, we present the systematic development of mechanically enhanced triple interpenetrating polymer network (Tri-IPN) hydrogels with Young’s moduli rivaling those of natural load-bearing tissues. To incorporate the third network, the PEG-DA hydrogel was immersed in an acrylic amide monomer solution containing 2% v/v photoinitiator solution and 1% v/v TEGDMA as a crosslinking agent for 24 h. These materials attain "biomimetic" values for initial Young’s modulus in addition to high tensile strength and water content, low pH respondent. As such, they are promising new candidates for artificial replacement of natural tissues such as the cornea, cartilage, and other load-bearing structures. |
| 저자 |
박상필, 이우진, 이열, 김대년, 장은지, 박새미, 고원건
|
| 소속 |
연세대 |
| 키워드 |
Hydrogel; Artificial tissue; Triple network
|
| E-Mail |
|
