| 초록 |
Block copolymers can self-assemble into various structure(ex) micelle, vesicle) in a selective solvent. In particular, polyethylene oxide (PEO) is widely used as hydrophilic block due to non-toxicity and the ability to form hydrogen bonding with water. Recently, lower critical solution temperature (LCST) behavior of aliphatic polyether has been investigated to apply for temperature responsive materials including drug delivery and tissue engineering. In this study, polyether based diblock copolymers have been synthesized including PEO for hydrophilic block and poly(ethyl glycidyl ether-ran-isopropyl glycidyl ether) (P(EGE-r-iPGE)) for hydrophobic block, respectively. The fraction of EGE in the hydrophobic block controls LCST temperature for the fixed degree of polymerization (DP), resulting in critical micelle temperature (CMT) of the diblock copolymer micelles in aqueous solution. Systematic modification of CMT and the micellar structure are investigated using DLS and SAXS. |
