| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Achilles tendon regeneration with porous PLCL scaffolds using dynamic tensile stimulation |
| 초록 |
At present the therapeutic options to treat damaged tendons or ligaments include autograft, allograft, or prosthetic devices. However, there are many problems, such as donor site morbidity, harmful response from immune system, and poor biocompatibility. In this study, we seed tenocytes from the rabbit tendon onto biodegradable porous PLCL[(poly lactide-co-ε-caprolactone)] scaffolds with excellent mechanical properties and biological interactions and cultured in the bioreactor which mimics the environment surroundings of the tendon. And then, we evaluate degree of neo-tissue regeneration in terms of mechanical properties, cell proliferation, and histology observation. |
| 저자 |
이종만1, 태기융1, 김영하1, 김상헌2, 김수현2, Luigi Ambrosio3
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| 소속 |
1광주과학기술원, 2한국과학기술(연), 3Institute of Composite & Biomaterials |
| 키워드 |
Tendon; Tenocyte; PLCL; Bioreactor
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| E-Mail |
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