| 초록 |
We fabricated fibrous tubular scaffolds with cells in pockets using a combination of electrospinning and electrospraying methods. The polymer solution was electrospun onto a rotating drum for the production of fibrous structures, while the cell dispersion was simultaneously electrosprayed onto the same rotating drum. Electrospun fibers were aligned on a rotating drum using conductive wires, while electrosprayed cell dispersion created pockets with cells present within the scaffold. The orientation of the aligned fibers can be adjusted based on the position of the conductive wire, which is useful for mimicking various tissues. Through the combination of our electrospinning and electrospray methods, we were able to produce tubular scaffolds with ordered fibrous structures containing living cells, allowing the cells to infiltrate and grow for a long enough time to promote efficient tissue regeneration. |
