| 초록 |
Recently, smart controlled release system has attracted great interest for use in applications such as controlled release implants. Toward this goal, mesoporous silica nanoparticles(MSNs) have widely studied as responsive gate keepers with structural characteristics such as large surface area, highly uniform framework, and on-demand release. However, various nanovalves on MSNs in response to certain stimuli has rarely been reported owing to complicated processes. We report rapid and facile strategy for producing mechanochemically and electrochemically responsive nanocapsule using phenol-metal coordination and by applying ultrasound and voltage to nanocapsule, we can induce decomposition of metal organic bond and controlled drug release of gel-capsule composites. |
