화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center))
권호 24권 1호
발표분야 포스터-생체재료
제목 Fluorescence on-off system silver hybrid-polymer dot for bacteria detection and killing
초록 We studied an effective nanomaterial for the detection of bacteria and the measurement of antimicrobial activity using fluorescent polymer dots and silver nanoparticles. We developed a PVP@Ag:PD system that takes highly fluorescent form using catechol chemistry to avoid fluorescent reduction of PD-Ag due to FRET quenching. Positively charged PVP@Ag:PD promotes and aggregates with the bacteria surface which mostly negative charge, influencing the fluorescence of the system due to intermolecular interaction. Even at low concentrations, PVP@Ag:PD showed prominent and sensitive bacterial killing efficiency. Using this feature, we developed a system for detecting and killing bacteria that combines biosensors with antimicrobial activity. Thus, this system provides a possibility for future bacteria sensing and extermination. This was supported by Korea National University of Transportation in 2020.
저자 김슬기1, 조현훈1, 박성영1, 박남식2, 이기백1
소속 1한국교통대, 2넥스켐
키워드 Fluorescence polymer dot; Anti-bacteria; Bacteria detection; Biosensor
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