초록 |
The application of biotechnology remains as a challenge due to their low productivity by using naturally evolved enzymes. Synthetic biology allows to overcome this limitation via anthropologically designed enzymes for increase of productivity. Although many successes by single bacteria applying synthetic biology have been reported, microbial bioconversion is still short of industrial applications, especially in waste to value-added products conversion which requires the difficult and complex system. Here, we examined the bioconversion using defined and engineered microbial consortium for the conversion of waste materials (glycerol or CO) to bioelectricity or acetate, respectively. As a result, the synthetic microbial consortium allows the production of bioelectricity or acetate, which the individual species does not achieve. Although further optimization is required, this strategy and models are highly applicable for the bioconversion of refractory substrate for target product. |