초록 |
Polydiacetylene (PDA), one of the responsive polymer, is an attractive material for sensors, bio-imaging and drug delivery systems. This material exhibits blue-to-red color transition due to the external stimuli. By assigning this material to supported lipid bilayer (SLB) platform, it delivers selectivity in bio-molecular detection. To investigate its time-dependent nanoscale phase behavior, we adapted computational chemistry. Especially, coarse grained molecular dynamic simulation has aimed at simulating the behavior of complex system. In this presentation, we present a crucial role of components in regulating the degree of phase coexistence, which can determine detection capability against antimicrobial peptide. |