화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO))
권호 44권 1호
발표분야 콜로이드 및 분자조립 부문위원회
제목 Regulating Gel-Phase Growth in Supported Lipid-Diacetylene Complex Bilayer: Molecular Interpretation via Computational Chemistry
초록 Polydiacetylene (PDA), one of the responsive polymer, is an attractive material for sensors, bio-imaging and drug delivery systems. This material exhibits blue-to-red color transition due to the external stimuli. By assigning this material to supported lipid bilayer (SLB) platform, it delivers selectivity in bio-molecular detection. To investigate its time-dependent nanoscale phase behavior, we adapted computational chemistry. Especially, coarse grained molecular dynamic simulation has aimed at simulating the behavior of complex system. In this presentation, we present a crucial role of components in regulating the degree of phase coexistence, which can determine detection capability against antimicrobial peptide.
저자 정우혁, 황지민, 이상엽, 안동준
소속 고려대
키워드 coarse grained molecular dynamics; supported lipid bilayer functionalized by polydiacetylene; gel phase nanodomain formation
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