학회 | 한국고분자학회 |
학술대회 | 2002년 가을 (10/11 ~ 10/12, 군산대학교) |
권호 | 27권 2호, p.78 |
발표분야 | 의료용 고분자 부문위원회 |
제목 | Comparison of hepatocytes behaviors between galactose-carrying natural polymer and synthetic polymer |
초록 | Proliferation, differentiation and functions of hepatocytes are regulated by the extracellular matrix(ECM). Natural ECMs have been revealed to control spreading, migration, adhesion and proliferation of hepatocytes. Synthetic ECMs replace many functions of the natural ECM, organizing cells into a three dimensional architecture, providing mechanical integrity to the new tissue. In this study, we compared hepatocytes behaviors between galactose-carrying natural polymer, tamarind seed xyloglucan and galactose-carrying polystyrene, poly(N-p-vinylbenzyl-4-o-β-D-galactopyranosyl-D-gluconamide)(PVLA). The effects of polymer concentration on morphology of hepatocytes, temperature, calcium and magnesium ion on hepatocytes attachment were performed. |
저자 | 조종수1, 서석진2, M. Shirakawa*3, T. Akaike**4 |
소속 | 1서울대, 2*Dainippon Pharmaceutical Co. Ltd., 3Japan, 4**Tokyo Institute of Technology |
키워드 | |